Lab Updates
Patient Impact
Autosomal recessive polycystic kidney disease is a severe kidney disease in children with a known therapeutic target 窶・but advancing toward drug development requires resources that current federal funding mechanisms do not easily support. Learn why human kidney organoids are uniquely suited for this research and how philanthropic support can help.
Research Highlight
Our lab uses human kidney organoids to investigate how kidney cells respond to injury and activate repair pathways. These models help us study human kidney biology in controlled experimental systems and may support the discovery of new therapeutic strategies.
Technology Spotlight
Kidney organoids contain complex three-dimensional structures. AI-assisted imaging and quantitative analysis allow us to measure organoid phenotypes more consistently and at greater scale, supporting drug discovery and disease modeling.
Behind the Science
Organoid-on-chip platforms allow kidney organoids to experience fluid flow and other physical cues relevant to kidney physiology. These systems can help model genetic kidney diseases such as polycystic kidney disease and support therapeutic discovery.